Searchable abstracts of presentations at key conferences in endocrinology

ea0049gp199 | Thyroid 1 | ECE2017

Cardiovascular risk factors in patients with autoimmune thyroiditis

Neves Joao Sergio , Cunha Catarina , Neves Celestino , Oliveira Sofia Castro , Sokhatska Oksana , Dias Camila , Esteves Cesar , Pereira Miguel , Medina Jose Luis , Delgado Luis , Carvalho Davide

Background: Overt thyroid dysfunction is associated with an increased cardiovascular risk. The impact of subclinical hypothyroidism and autoimmunity in the increased cardiovascular risk remains controversial. Aim: To evaluate the interrelations between thyroid function, thyroid autoimmunity and cardiovascular risk factors, in patients with autoimmune thyroiditis (AIT).Methods: 353 subjects with AIT were evaluated. We defined three groups based on TSH lev...

ea0049gp229 | Thyroid Cancer | ECE2017

Trends in papillary microcarcinoma prevalence in North of Portugal

Pereira Teresa Alves , Amado Ana , Gouveia Patricia , Castro Rosa , da Costa Antonio Moreira , de Carvalho Andre Couto , Freitas Claudia , Borges Fatima

Introduction and Objectives: The incidence of thyroid cancer has increased worldwide. This increase has been attributed to more diagnosed papillary thyroid microcarcinomas. The purpose of this study was to analyse the growing trend of first appointments in our Thyroid Cancer Unit, namely patients with papillary microcarcinomas.Methods: We performed a retrospective study based on the patients diagnosed with thyroid cancer between 1960 and 2016. We divided...

ea0049ep53 | Adrenal cortex (to include Cushing's) | ECE2017

Adrenal cushing’s syndrome surprisingly unveiling breast cancer

Neves Joao Sergio , Oliveira Ana Isabel , Souteiro Pedro , Oliveira Sofia Castro , Baldaia Helena , Melo Daniel , Neves Celestino , Freitas Paula , Carvalho Davide

Introduction: Cushing’s syndrome is an endocrinopathy characterized by glucocorticoids excess. Adrenalectomy is the recommend treatment for unilateral adrenal Cushing’s syndrome and is usually associated with resolution of the disease.Clinical Case: A 54-year old woman with central obesity (BMI 34.3 kg/m2), diabetes and hypertension had a left adrenal mass of 15 mm and characteristics suggestive of adenoma (Hounsfield unit of <10...

ea0049ep54 | Adrenal cortex (to include Cushing's) | ECE2017

Giant adrenal tumor in a patient admitted for fever

Neves Joao Sergio , Teles Luis , Souteiro Pedro , Oliveira Sofia Castro , Oliveira Ana Isabel , Fernandes Ana Catarina , Damasceno Margarida , Graca Luisa , Rodrigues Elisabete , Neves Celestino , Freitas Paula , Carvalho Davide

Introduction: Adrenal tumors are usually detected due to clinical manifestations of hormonal hypersecretion or incidental findings on imaging evaluation. Although most incidentalomas are non-functioning adenomas, it is important to appropriately evaluate such masses to exclude hormonal excess or malignancy.Case description: An 81-year old male was admitted to our hospital for fever with 15 days of evolution. The patient also presented chills and loss of ...

ea0049ep406 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Episodes of poorly controlled diabetes in 1486 patients admitted in Orthopedic Surgery and Traumatology

Vega Maria Molina , Mora Pilar Losada , Castro Alfonso M Garrido , Almeida Jose M Garcia , Linares Juan L Carrillo , Fuentes Miguel Damas , Garcia Carmen Rodriguez , Perdigones Cristina Diaz

Introduction: Episodes of poorly controlled diabetes (DM) are one of the most frequent medical complications during hospitalization in the elderly population.Objectives: To analyze the prevalence of episodes of diabetic decompensation in patients admitted in Orthopedic Surgery and Traumatology (OST) area.Material and methods: Descriptive analysis of patients admitted to OST Service who presented abnormally high or decreased blood g...

ea0049ep407 | Diabetes (to include epidemiology, pathophysiology) | ECE2017

Episodes of poorly controlled diabetes in 173 patients admitted in Vascular Surgery

Vega Maria Molina , Mora Pilar Losada , Castro Alfonso M Garrido , Almeida Jose M Garcia , Linares Juan L Carrillo , Fuentes Miguel Damas , Garcia Carmen Rodriguez , Perdigones Cristina Diaz

Introduction: Episodes of poorly controlled diabetes (DM) are one of the most frequent medical complications during hospitalization in the elderly population.Objetives: To analyze the prevalence of episodes of diabetic decompensation in patients admitted to the area of Vascular Surgery and Angiology (VS).Material and methods: Descriptive analysis of patients admitted to the VS Service who presented abnormally high or decreased bloo...

ea0049ep576 | Diabetes complications | ECE2017

Severe diabetic gastroparesis – two cases of challenging treatment

Souteiro Pedro , Oliveira Sofia Castro , Neves Joao Sergio , Santos-Antunes Joao , Bettencourt-Silva Rita , Belo Sandra , Neves Celestino , Freitas Paula , Queiros Joana , Esteves Cesar , Carvalho Davide

Introduction: Gastroparesis is defined by a delayed gastric emptying without mechanical obstruction. It can be a debilitating complication of diabetes that is poorly understood and has limited therapeutic options.Case reports: 1st case - We report the case of a 34-year-old woman with type 1 diabetes mellitus (T1DM) with diabetic nephropathy and gastroparesis, and a reasonable glycaemic control...

ea0049ep714 | Obesity | ECE2017

Concern about body image, impulsiveness and personality traits in the morbidly obese before bariatric surgery and in patients who have undergone surgery

Mateo-Gavira Isabel , Medina-Rivero Daniel , Novalbos-Ruiz Jose Pedro , Rodriguez-Martin Amelia , Santi-Cano Maria Jose , de Castro D Ogalla , Aguilar-Diosdado Manuel

Objectives: To analyse the levels of anxiety, depression, impulsiveness, bulimic behaviour, concern about body image and the quality of life of patients included in the care process following bariatric surgery, in our field.Methods: Observational study of the patients included in the care process for bariatric surgery at University Hospital Puerta del Mar. Two cohorts were identified according to their situation before or after surgery. Studies were made...

ea0049ep725 | Paediatric endocrinology | ECE2017

Congenital hyperinsulinism in two siblings due to the same ABCC8 mutation: the clinical importance of an early diagnosis and treatment

Santos Francisco Sousa , Simoes Helder , Castro-Feijoo Lidia , Rodriguez Paloma Cabanas , Fernandez-Marmiesse Ana , Fiano Rebeca Saborido , Rego Teresa , Carracedo Angel , Conde Jesus Barreiro

Introduction: Congenital hyperinsulinism (CHI) is a heterogenous disease caused by insulin secretion regulatory defects, being ABCC8/KCNJ11 the most commonly affected genes. It can present as focal or diffuse pancreatic disease, which is mainly determined by the genotype. Diazoxide is the first-line medication in diffuse cases, however many do not respond satisfactory. Second-line options include somatostatin analogues and surgery, which is curative in case of focal CHI.<p...

ea0049ep791 | Endocrine tumours and neoplasia | ECE2017

Polyglandular autoimmune syndrome type III b

Vaz de Castro Raquel , Maria Aragues Jose , Ferreira Florbela , Gomes Vania , Wessling Ana , Tavares Lurdes , Ribeiro Joana , Alves Irina , Camilo Fernandes Afonso , Joao Bugalho Maria

: We report the case of a 57-year-old female diagnosed with Grave’s disease fifteen years before (TSH <0.001 U/ml; FT4 2.3 ng/dl; FT3 7.2 ng/dl, TSAbs 17 U/l). Persistency of hyperthyroidism despite antithyroid therapy led to total thyroidectomy three years after the diagnosis. Thereafter, thyroid function remained normal under hormonal replacement with levothyroxine. The patient had also been diagnosed with Pernicious Anemia at 47 years of age after investigation for...